SCHEMBL8995310

SCHEMBL8995310

Nc1ccc2c(c1)C(=O)N(c1ccccc1N1C(=O)c3ccc(N)cc3C1=O)C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.62
NFKB1 P19838 1/20 0.62
PMP22 Q01453 1/20 0.62
ANPEP P15144 2/20 0.60
DPP4 P27487 1/20 0.60
ALDH1A1 P00352 5/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
TSHR P16473 3/20 0.59
CASP1 P29466 3/20 0.59
HSD17B10 Q99714 2/20 0.59
CASP7 P55210 1/20 0.59
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPK1 P28482 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
TP53 P04637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
PTPRC P08575 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10658930 0.88 ANPEP (0.69) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL9468774 0.87 ANPEP (0.59) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL28445363 0.85 POLB (0.71) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL4782142 0.83 ALDH1A1 (0.72) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL8995319 0.80 CASP1 (0.86) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL18917454 0.79 CYP3A4 (0.65) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL9468849 0.79 NPC1 (0.67) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL4649466 0.79 POLB (0.65) CYP3A4NFKB1PMP22ALDH1A1CASP1
SCHEMBL9566650 0.78 CASP1 (0.83) CYP3A4NFKB1PMP22ANPEPDPP4
SCHEMBL9566664 0.78 NPC1 (0.65) CYP3A4NFKB1PMP22ANPEPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0600069-B1 ETHERIMIDEIMIDE/ETHERIMIDE COPOLYMER KOREA RES INST CHEM TECH (KR) 1996-11-13 EP disclosed
US-5569738-A Melt processable etherimideimide/etherimide copolymer KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1996-10-29 US disclosed
EP-0600069-A1 NOVEL ETHERIMIDEIMIDE/ETHERIMIDE COPOLYMER. KOREA RES INST CHEM TECH (KR) 1994-06-08 EP disclosed
WO-1993024556-A1 NOVEL ETHERIMIDEIMIDE/ETHERIMIDE COPOLYMER KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-09 WO disclosed