Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | CASP1 | P29466 | 2/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.63 |
| ▸ | ANPEP | P15144 | 2/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468849 | 0.95 | NPC1 (0.67) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL13910988 | 0.89 | KMT2A (0.67) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL6581387 | 0.88 | ALDH1A1 (0.59) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL4782142 | 0.87 | ALDH1A1 (0.72) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL9453218 | 0.87 | MEN1 (0.57) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL9566635 | 0.87 | KMT2A (0.57) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL14901036 | 0.87 | ALDH1A1 (0.67) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL9566591 | 0.87 | NPC1 (0.58) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL12731813 | 0.85 | BRD4 (0.59) | NPC1RAB9AALDH1A1TSHRCASP1 | |
| SCHEMBL8995319 | 0.85 | CASP1 (0.86) | NPC1RAB9AALDH1A1TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530707-A1 | Method for preparing polyamide-imides | EASTMAN KODAK COMPANY (US) | 1993-03-10 | — | — | EP | claimed |
| EP-0530707-A1 | Method for preparing polyamide-imides | EASTMAN KODAK COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| US-4946235-A | Nonlinear optical waveguide device | EASTMAN KODAK COMPANY (US) | 1990-08-07 | — | — | US | disclosed |
| WO-1990005722-A1 | PHTHALIMIDE COMPOUNDS FOR FORMING AMORPHOUS LAYERS BY VACUUM DEPOSITION | EASTMAN KODAK COMPANY (US) | 1990-05-31 | — | — | WO | disclosed |