Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP10 | P09238 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416798 | 1.00 | ITGB3 (0.56) | ITGB3ITGA2BGRIA1CHRNB2CHRNB4 | |
| SCHEMBL7425557 | 0.93 | ITGB3 (0.62) | ITGB3ITGA2BGRIA1CHRNB2CHRNB4 | |
| SCHEMBL7425539 | 0.93 | ITGB3 (0.62) | ITGB3ITGA2BGRIA1CHRNB2CHRNB4 | |
| SCHEMBL7414657 | 0.87 | FOLH1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7415256 | 0.87 | FOLH1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7417654 | 0.87 | FOLH1 (0.53) | ITGB3ITGA2BF10 | |
| SCHEMBL7431042 | 0.85 | ITGB3 (0.70) | ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7417445 | 0.83 | F2 (0.54) | F10 | |
| SCHEMBL7417435 | 0.83 | F2 (0.54) | F10 | |
| SCHEMBL7417133 | 0.83 | MMP2 (0.50) | ITGB3ITGA2BGRIA1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |