Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995542 | 0.86 | NAMPT (0.45) | NAMPTKMT2AHPGDALDH1A1CYP2D6 | |
| SCHEMBL8995539 | 0.86 | NAMPT (0.45) | NAMPTKMT2AHPGDALDH1A1CYP2D6 | |
| SCHEMBL8995562 | 0.74 | CTSS (0.52) | — | |
| SCHEMBL8995548 | 0.74 | CTSS (0.52) | — | |
| SCHEMBL7423272 | 0.74 | CTSS (0.52) | — | |
| SCHEMBL7423600 | 0.74 | CTSS (0.55) | KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL7423594 | 0.74 | CTSS (0.55) | KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL8995569 | 0.74 | CTSS (0.55) | KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL7419202 | 0.72 | NPSR1 (0.59) | L3MBTL1KMT2AHPGDALDH1A1CYP2C9 | |
| SCHEMBL7419206 | 0.72 | NPSR1 (0.59) | L3MBTL1KMT2AHPGDALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |