Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995539 | 1.00 | NAMPT (0.45) | NAMPTMMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL8995566 | 0.86 | NAMPT (0.44) | NAMPTKMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL8995531 | 0.81 | ITGB3 (0.51) | — | |
| SCHEMBL8995540 | 0.80 | KMT2A (0.38) | KMT2AALDH1A1HPGDCYP2D6CYP2C9 | |
| SCHEMBL7421065 | 0.75 | ITGB3 (0.55) | NAMPTKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL7421070 | 0.75 | ITGB3 (0.55) | NAMPTKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL7383847 | 0.73 | EPHX2 (0.57) | NAMPTCCR3 | |
| SCHEMBL7417133 | 0.70 | MMP2 (0.50) | NAMPTMMP12MMP13LMNATSHR | |
| SCHEMBL8995577 | 0.69 | MMP12 (0.39) | NAMPTMMP12MMP13KMT2ACYP2D6 | |
| SCHEMBL7365013 | 0.68 | FFAR1 (0.60) | MMP12MMP13TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552431-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5424334-A | Peptide mimetic compounds useful as platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-06-13 | — | — | US | disclosed |