Saccharin

Saccharin

SCHEMBL789140

C=C(C)C(=O)O.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.71
CA9 Q16790 7/20 0.71
CA2 P00918 6/20 0.71
CA1 P00915 2/20 0.71
KDM4E B2RXH2 2/20 0.71
USP2 O75604 1/20 0.71
LMNA P02545 1/20 0.71
BCHE P06276 1/20 0.71
CA4 P22748 1/20 0.71
CA6 P23280 1/20 0.71
CA5A P35218 1/20 0.71
CA7 P43166 1/20 0.71
KMT2A Q03164 1/20 0.71
CA14 Q9ULX7 1/20 0.71
CA5B Q9Y2D0 1/20 0.71
ALDH1A1 P00352 3/20 0.48
HSD11B1 P28845 1/20 0.48
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
ALPL P05186 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL27876263 0.90 CA12 (0.76) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL10962118 0.90 CA12 (0.81) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL21951955 0.89 CA12 (0.65) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL9636265 0.88 CA12 (0.79) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL29141814 0.88 CA12 (0.79) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27642958 0.88 CA12 (0.85) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28045129 0.88 CA12 (0.92) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27848168 0.86 CA12 (0.88) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28334570 0.86 CA12 (0.88) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL11600574 0.85 CA12 (0.79) CA12CA9CA2CA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024133662-A1 CORE-SHELL CAPSULES OF METHACRYLATE OR ACRYLATE MODIFIED POLYSACCHARIDES FUNDACIÓN CIDETEC (ES) 2024-06-27 WO claimed
US-20230102859-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2023-03-30 US claimed
WO-2021122942-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2021-06-24 WO claimed
WO-2024133662-A1 CORE-SHELL CAPSULES OF METHACRYLATE OR ACRYLATE MODIFIED POLYSACCHARIDES FUNDACIÓN CIDETEC (ES) 2024-06-27 WO disclosed
WO-2024133662-A1 CORE-SHELL CAPSULES OF METHACRYLATE OR ACRYLATE MODIFIED POLYSACCHARIDES FUNDACIÓN CIDETEC (ES) 2024-06-27 WO disclosed
US-20230293306-A1 BIONIC TISSUE STENT, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SINOBIOPRINT (SHANGHAI) BIOTECH LTD. (CN) 2023-09-21 US disclosed
US-20230102859-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2023-03-30 US disclosed
US-20230102859-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2023-03-30 US disclosed
WO-2021122942-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2021-06-24 WO disclosed
WO-2021122942-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS FUNDACIÓN CIDETEC (ES) 2021-06-24 WO disclosed
US-20210149307-A1 UNDERLAYER FILM-FORMING COMPOSITION, PATTERN-FORMING METHOD, AND COPOLYMER FOR FORMING UNDERLAYER FILM USED FOR PATTERN FORMATION Oji Holdings Corporation (JP) 2021-05-20 US disclosed
EP-3654102-A1 UNDERLAYER FILM-FORMING COMPOSITION, PATTERN-FORMING METHOD, AND COPOLYMER FOR FORMING UNDERLAYER FILM USED FOR PATTERN FORMATION Oji Holdings Corporation (JP) 2020-05-20 EP disclosed
CN-107921237-A Sympathetic nerve cardiopulmonary neural modulation system and method 反射医学公司 2018-04-17 CN disclosed
US-8557893-B2 Substituted saccharide compounds and dental compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-10-15 US disclosed
EP-2616476-A2 SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS 3M Innovative Properties Company (US) 2013-07-24 EP disclosed
US-20130164709-A1 SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-06-27 US disclosed
WO-2012036838-A2 SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130164709-A1 SUBSTITUTED SACCHARIDE COMPOUNDS AND DENTAL COMPOSITIONS SI, ACMSD, SORD CA12 104/4885CA9 175/4885CA2 481/4885
US-20230102859-A1 NATURAL ORIGIN STABILIZER FOR OIL IN WATER EMULSIONS NPM1, MSN, SNRNP200 CA12 2733/4885CA9 2744/4885CA2 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.