Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719950 | 0.86 | MGLL (0.88) | MGLLHSP90AA1TLR9FAAHNR1H2 | |
| SCHEMBL30398083 | 0.84 | MGLL (1.00) | MGLLHSP90AA1TLR9FAAHNR1H2 | |
| SCHEMBL3768557 | 0.84 | MGLL (1.00) | MGLLHSP90AA1TLR9FAAHNR1H2 | |
| SCHEMBL2900895 | 0.78 | MGLL (0.73) | MGLLHSP90AA1TLR9FAAHNR1H2 | |
| SCHEMBL6832688 | 0.76 | TLR9 (0.76) | MGLLHSP90AA1TLR9FAAHALDH1A1 | |
| SCHEMBL1087460 | 0.76 | HSP90AA1 (0.58) | MGLLHSP90AA1TLR9PIN1FAAH | |
| SCHEMBL571682 | 0.75 | HSP90AA1 (1.00) | MGLLHSP90AA1FAAHALDH1A1TDP1 | |
| SCHEMBL28616908 | 0.74 | MGLL (0.73) | MGLLHSP90AA1TLR9FAAHALDH1A1 | |
| SCHEMBL12367620 | 0.72 | ALDH1A1 (0.65) | ALDH1A1TDP1HSD17B10ALOX15TSHR | |
| SCHEMBL28624878 | 0.71 | MGLL (0.73) | MGLLHSP90AA1TLR9FAAHNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570825-B1 | Tire sidewall composition containing silica having low PH | GOODYEAR TIRE & RUBBER (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0570825-A1 | Tire sidewall composition containing silica having low PH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5244028-A | Natural rubber or polybutadiene, silica, antidegradation agent, carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5216049-A | A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |