Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 7/20 | 0.58 |
| ▸ | THRB | P10828 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996090 | 0.83 | FTO (0.73) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996006 | 0.81 | FTO (0.59) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996019 | 0.80 | FTO (0.76) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8995993 | 0.80 | FTO (0.76) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996015 | 0.79 | FTO (0.74) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996086 | 0.79 | FTO (0.73) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996239 | 0.79 | FTO (0.73) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996010 | 0.78 | FTO (0.73) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL8996037 | 0.77 | EGFR (0.76) | FTOTP53THRBSMN1; SMN2PKM | |
| SCHEMBL9065481 | 0.76 | FTO (0.69) | FTOTP53THRBSMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |