Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996086 | 1.00 | FTO (0.73) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996027 | 0.84 | FTO (1.00) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996033 | 0.79 | FTO (0.61) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996053 | 0.79 | FTO (0.78) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996037 | 0.78 | EGFR (0.76) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996006 | 0.75 | FTO (0.59) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8995993 | 0.74 | FTO (0.76) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996019 | 0.74 | FTO (0.76) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996015 | 0.73 | FTO (0.74) | FTOMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8996090 | 0.72 | FTO (0.73) | FTOMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |