Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.56 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.56 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21972740 | 0.84 | NPC1 (0.59) | MAPTHTTLMNANPC1MEN1 | |
| SCHEMBL9819103 | 0.83 | ACP1 (0.53) | MAPTHTTHSD17B10MEN1KMT2A | |
| SCHEMBL5141417 | 0.83 | MEN1 (0.71) | MAPTHTTLMNAHSD17B10NPC1 | |
| SCHEMBL8650426 | 0.82 | HTT (0.61) | MAPTHTTHSD17B10MEN1KMT2A | |
| SCHEMBL11421956 | 0.81 | HTT (0.59) | MAPTHTTLMNAHSD17B10NPC1 | |
| SCHEMBL8623425 | 0.81 | HSD17B10 (0.63) | HTTHSD17B10NPC1MEN1KMT2A | |
| SCHEMBL14517868 | 0.81 | HSD17B10 (0.59) | HTTLMNAHSD17B10MEN1KMT2A | |
| SCHEMBL1260084 | 0.81 | KMT2A (0.70) | MAPTHTTLMNAHSD17B10NPC1 | |
| SCHEMBL9320423 | 0.80 | CA1 (0.56) | MAPTHTTLMNAHSD17B10MEN1 | |
| SCHEMBL1618221 | 0.80 | ALDH1A1 (0.64) | MAPTHTTLMNAHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0209028-A2 | Use of the 3-iminoisoindoline derivatives, and 3-iminoisoindoline derivatives | BASF Aktiengesellschaft (DE) | 1987-01-21 | — | — | EP | disclosed |
| US-4438092-A | 5-Amino-N-(3-chloro- 2-methyl-, or 2-fluorophenyl)-1,3-dimethyl-1H-pyrazole-4-carboxamides and use as an anti-convulsant | WARNER-LAMBERT COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4346097-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1982-08-24 | — | — | US | disclosed |