Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137005 | 0.84 | ABL1 (0.51) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL8996041 | 0.83 | MAPT (0.59) | CYP1A2CYP2C19HTTHSD17B10MEN1 | |
| SCHEMBL19277777 | 0.82 | GAA (0.49) | ACP1L3MBTL1HTTMEN1KMT2A | |
| SCHEMBL6568660 | 0.82 | ABL1 (0.50) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL1618221 | 0.81 | ALDH1A1 (0.64) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL11435532 | 0.81 | CA12 (0.50) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL10868124 | 0.80 | RAB9A (0.50) | L3MBTL1CYP1A2CYP2C19CA12CA1 | |
| SCHEMBL8072208 | 0.79 | CA12 (0.51) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL21731949 | 0.79 | HTT (0.41) | ACP1L3MBTL1FABP4CYP1A2CYP2C19 | |
| SCHEMBL11122026 | 0.78 | CA12 (0.73) | CYP1A2CYP2C19CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034410-A | Nitrile and oxo containing amides or thioamides | SYNTEX (U.S.A.) INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4400507-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| US-4262120-A | YELLOW TO ORANGE SHADES OF GOOD FASTNESS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |