Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137571 | 0.84 | MAOB (0.40) | ANPEPMAOBSLC6A2TAAR1MAOA | |
| SCHEMBL6137564 | 0.84 | MAOB (0.40) | ANPEPMAOBSLC6A2TAAR1MAOA | |
| SCHEMBL3299433 | 0.83 | MAOB (0.40) | ANPEPMAOBSMN1; SMN2L3MBTL1SLC6A2 | |
| SCHEMBL1667041 | 0.81 | FAAH (0.41) | CTSSL3MBTL1SIGMAR1 | |
| SCHEMBL12398347 | 0.80 | FAAH (0.43) | SIGMAR1 | |
| SCHEMBL13594158 | 0.78 | SIGMAR1 (0.44) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL9621418 | 0.76 | TRPA1 (0.40) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL388942 | 0.76 | EPHX1 (0.48) | ANPEPSLC6A2TAAR1MAOASLC6A4 | |
| SCHEMBL27528003 | 0.75 | SLC6A4 (0.39) | CTSLCTSBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3980781 | 0.74 | MAOB (0.43) | ANPEPMAOBSLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |