Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573606 | 0.91 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL9573610 | 0.91 | KMT2A (0.68) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8995992 | 0.90 | FTO (0.61) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8995999 | 0.90 | EGFR (0.64) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8996039 | 0.89 | FTO (0.56) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8996053 | 0.88 | FTO (0.78) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8995993 | 0.86 | FTO (0.76) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8996019 | 0.86 | FTO (0.76) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8996241 | 0.80 | FTO (0.58) | KMT2AMEN1MAPTALDH1A1FTO | |
| SCHEMBL8996015 | 0.79 | FTO (0.74) | KMT2AMEN1MAPTALDH1A1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |