Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.78 |
| ▸ | EGFR | P00533 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16160370 | 0.89 | FTO (0.76) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL8996055 | 0.88 | KMT2A (0.64) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL8996027 | 0.88 | FTO (1.00) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL8995999 | 0.86 | EGFR (0.64) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL8995992 | 0.86 | FTO (0.61) | FTOMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8996039 | 0.83 | FTO (0.56) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL29813596 | 0.80 | EGFR (0.72) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL5819801 | 0.79 | EGFR (0.83) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL29813583 | 0.79 | EGFR (0.73) | FTOEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL8996239 | 0.79 | FTO (0.73) | FTOEGFRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5514711-A | ANTICARCINOGENIC AGENTS; SIDE EFFECT REDUCTION | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0537742-A2 | Styrene derivatives | Mitsubishi Chemical Corporation (JP) | 1993-04-21 | — | — | EP | disclosed |