Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996089 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL8996085 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL22887482 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL29496403 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL11062788 | 0.84 | KMT2A (0.52) | ALDH1A1CYP1A1CYP1A2CYP1B1CYP11B1 | |
| SCHEMBL11062783 | 0.84 | KMT2A (0.52) | ALDH1A1CYP1A1CYP1A2CYP1B1CYP11B1 | |
| SCHEMBL11071917 | 0.84 | KMT2A (0.52) | ALDH1A1CYP1A1CYP1A2CYP1B1CYP11B1 | |
| SCHEMBL27279163 | 0.84 | RAB9A (0.52) | CYP1A1CYP1A2CYP1B1LMNACYP11B1 | |
| SCHEMBL13912518 | 0.83 | CYP1A1 (0.68) | ALDH1A1CYP1A1CYP1A2CYP1B1LMNA | |
| SCHEMBL30644217 | 0.83 | PTPN1 (0.58) | ALDH1A1LMNAPTPN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563151-A | PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |