Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506291 | 0.89 | POLL (0.49) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7477968 | 0.88 | KDM4E (0.52) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13475464 | 0.88 | KDM4E (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1829004 | 0.88 | KDM4E (0.50) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9621313 | 0.82 | ALDH1A1 (0.51) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL382674 | 0.81 | TOP1 (0.56) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30610021 | 0.81 | TOP1 (0.56) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3273673 | 0.78 | KMT2A (0.50) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4226377 | 0.78 | RAB9A (0.57) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7709655 | 0.76 | TYMS (0.56) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| US-5294375-A | Thermochromic materials | POLAROID CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5006651-A | Rheumatic diseases, bone disorders | HOFFMAN-LA ROCHE INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0276436-A1 | Phosphinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-08-03 | — | — | EP | disclosed |
| US-4289781-A | Anti-psychotic phthalimidine derivatives | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1981-09-15 | — | — | US | disclosed |
| EP-0026749-A1 | Phthalimidine derivatives and pharmaceutical compositions containing them | Astra Läkemedel Aktiebolag (SE) | 1981-04-08 | — | — | EP | disclosed |
| US-4250007-A | Photocurable acrylic phosphate esters of epoxidized polybutadiene | UBE INDUSTRIES, LTD. (JP) | 1981-02-10 | — | — | US | disclosed |
| US-4032656-A | ANTIPROSTAGLANDIN ACTIVITY, ANTIDIARRHEA AGENTS | SMITHKLINE CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |