Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996601 | 0.84 | PDE5A (0.48) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL8996340 | 0.80 | KDM4E (0.54) | RAB9ANPC1KMT2AKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8996365 | 0.79 | KDM4E (0.53) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL8996422 | 0.79 | KMT2A (0.50) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL8996330 | 0.68 | AMY1A (0.54) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL11526060 | 0.68 | EGFR (0.63) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL11101186 | 0.67 | TTR (0.72) | RAB9ANPC1KMT2AKDM4EHPGD | |
| SCHEMBL5613348 | 0.67 | ALDH1A1 (0.73) | KMT2AKDM4EHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL12545953 | 0.66 | PDE5A (0.55) | RAB9ANPC1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8996409 | 0.66 | KDM4E (0.64) | KMT2AKDM4EHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |