Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814027 | 0.74 | NPSR1 (0.55) | FERMT2MAPTALDH1A1NPSR1POLB | |
| SCHEMBL8996432 | 0.72 | FERMT2 (0.56) | FERMT2CYP1A2ALDH1A1NPSR1POLB | |
| SCHEMBL8996413 | 0.72 | NOS2 (0.33) | SLC6A2SLC6A4FERMT2MAPTPKM | |
| SCHEMBL8869324 | 0.71 | ALDH1A1 (0.36) | FERMT2MAPTPKMCYP1A2ALDH1A1 | |
| SCHEMBL10806223 | 0.68 | GAA (0.44) | MAPTALDH1A1POLBGAA | |
| SCHEMBL29176166 | 0.66 | KMT2A (0.44) | MAPTCYP1A2ALDH1A1NPSR1POLB | |
| SCHEMBL13285566 | 0.64 | MRGPRX4 (0.49) | ALDH1A1 | |
| SCHEMBL7289181 | 0.61 | NPSR1 (0.58) | FERMT2MAPTALDH1A1NPSR1POLB | |
| SCHEMBL15415606 | 0.61 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL20673500 | 0.61 | FERMT2 (0.50) | FERMT2MAPTCYP1A2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550143-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1996-08-27 | — | — | US | disclosed |
| EP-0572308-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-12-01 | — | — | EP | disclosed |