Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814027 | 0.90 | NPSR1 (0.55) | FERMT2ALDH1A1GAANPSR1TSHR | |
| SCHEMBL3871191 | 0.81 | FERMT2 (0.56) | FERMT2ALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL7960481 | 0.78 | FERMT2 (0.56) | FERMT2ALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL7289181 | 0.78 | NPSR1 (0.58) | FERMT2ALDH1A1GAANPSR1TSHR | |
| SCHEMBL8869324 | 0.77 | ALDH1A1 (0.36) | FERMT2ALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL4743774 | 0.76 | ALDH1A1 (0.67) | FERMT2ALDH1A1GAANPSR1TSHR | |
| SCHEMBL7973719 | 0.73 | ALDH1A1 (0.85) | FERMT2ALDH1A1NPSR1CYP1A2TSHR | |
| SCHEMBL8996413 | 0.72 | NOS2 (0.33) | FERMT2ALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL8996438 | 0.72 | SLC6A2 (0.36) | FERMT2ALDH1A1GAANPSR1CYP1A2 | |
| SCHEMBL30817040 | 0.72 | FERMT2 (1.00) | FERMT2CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550143-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1996-08-27 | — | — | US | disclosed |
| EP-0572308-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-12-01 | — | — | EP | disclosed |