Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715959 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL7718907 | 0.78 | L3MBTL1 (0.41) | TSHRCYP3A4ALOX15TDP1MGAM | |
| SCHEMBL11328711 | 0.76 | KMT2A (0.43) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL7718951 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL3584803 | 0.72 | GABRP (0.47) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL11373686 | 0.72 | GABRP (0.42) | ALDH1A1TSHRGABRPGABRDGABRA1 | |
| SCHEMBL7718880 | 0.71 | L3MBTL1 (0.42) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL7718953 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL7716766 | 0.70 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4ALOX15TDP1 | |
| SCHEMBL10134701 | 0.69 | GABRP (0.39) | ALDH1A1TSHRCYP3A4ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480873-A | ARTHRITIS | LILLY INDUSTRIES LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0570091-A1 | Anthraquinone derivatives, process for their preparation and their use as medicaments | LILLY INDUSTRIES LIMITED (GB) | 1993-11-18 | — | — | EP | disclosed |