SCHEMBL8996446

SCHEMBL8996446

Cc1ccc(CC(C)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.44
PGR P06401 1/20 0.44
NR3C2 P08235 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
SLC6A2 P23975 2/20 0.38
TRPA1 O75762 1/20 0.38
LMNA P02545 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
PYCR1 P32322 1/20 0.38
PSMB5 P28074 2/20 0.37
PSMB8 P28062 1/20 0.37
SLC6A4 P31645 1/20 0.36
CASR P41180 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546230 0.87 NR3C1 (0.43) NR3C1PGRNR3C2SLC6A2TRPA1
SCHEMBL3031236 0.79 KDM4E (0.47) NR3C1PGRNR3C2KDM4EALDH1A1
SCHEMBL6546939 0.78 PSMB5 (0.44) NR3C1PGRNR3C2KDM4EALDH1A1
SCHEMBL6546729 0.78 SIGMAR1 (0.44) SLC6A2SLC6A4CASR
SCHEMBL28263806 0.78 TSHR (0.42) NR3C1PGRNR3C2KDM4EALDH1A1
SCHEMBL9249660 0.77 KMT2A (0.44) LMNACASR
SCHEMBL20738712 0.76 TRPA1 (0.45) KDM4EALDH1A1SLC6A2TRPA1LMNA
SCHEMBL10894087 0.76 KDM4E (0.45) NR3C1PGRNR3C2KDM4EALDH1A1
SCHEMBL3634469 0.76 KDM4E (0.45) NR3C1PGRNR3C2KDM4EALDH1A1
Hydrochloric Acid SCHEMBL3638959 0.74 KDM4E (0.44) NR3C1PGRNR3C2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0508292-B1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN CO (JP) 1996-08-28 EP disclosed
US-5422027-A Drive fluid for rotational elements having a torque transmission relationship comprising a bicyclooctane; low viscosity; broad temperature range; automobile transmissions IDEMITSU KOSAN CO., LTD. (JP) 1995-06-06 US disclosed
US-5283384-A Low viscosity IDEMITSU KOSAN CO., LTD. (JP) 1994-02-01 US disclosed
EP-0508292-A1 Traction drive fluid, process for producing the same and bicyclo octane compound IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-14 EP disclosed