Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899647 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TDP1SMN1; SMN2TP53TSHR | |
| SCHEMBL8398671 | 0.98 | TDP1 (0.49) | ALDH1A1TDP1SMN1; SMN2TP53TSHR | |
| SCHEMBL28026694 | 0.98 | TDP1 (0.49) | ALDH1A1TDP1SMN1; SMN2TP53TSHR | |
| SCHEMBL27556368 | 0.95 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2TP53TSHR | |
| SCHEMBL27463698 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2TP53TSHRGPR35 | |
| Formaldehyde SCHEMBL27590299 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TP53TSHRGPR35 | |
| SCHEMBL22271648 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRKCNH2MAPT | |
| SCHEMBL4231830 | 0.83 | ALDH1A1 (0.58) | ALDH1A1TDP1SMN1; SMN2TP53TSHR | |
| SCHEMBL6549530 | 0.83 | TDP1 (0.50) | ALDH1A1TDP1TSHRGAATHRB | |
| SCHEMBL18688890 | 0.83 | TYR (0.57) | ALDH1A1TDP1SMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083577-A1 | Poly(Ethylene Oxide) Functionalization | SEEO, INC (US) | 2012-04-05 | — | — | US | claimed |
| US-20120083577-A1 | Poly(Ethylene Oxide) Functionalization | SEEO, INC (US) | 2012-04-05 | — | — | US | disclosed |