Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12105051 | 0.87 | KDM4E (0.47) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL11689296 | 0.84 | KDM4E (0.59) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL301403 | 0.84 | KDM4E (0.59) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL14822849 | 0.84 | KDM4E (0.59) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL5833342 | 0.83 | POLB (0.48) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL20548051 | 0.83 | POLB (0.48) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL6811019 | 0.83 | KDM4E (0.42) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL22361971 | 0.83 | POLB (0.48) | KDM4ELMNAPOLBAPEX1TDP1 | |
| Water SCHEMBL7734213 | 0.83 | KDM4E (0.57) | KDM4ELMNAPOLBAPEX1TDP1 | |
| SCHEMBL11801332 | 0.80 | KDM4E (0.42) | KDM4ELMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240543-B1 | BTK INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |
| US-12042788-B2 | Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis | THE UNIVERSITY OF CHICAGO (US) | 2024-07-23 | — | — | US | disclosed |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3461816-B1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20210053042-A1 | STRONGLY LEWIS ACIDIC METAL-ORGANIC FRAMEWORKS FOR CONTINUOUS FLOW CATALYSIS | NATIONAL SCIENCE FOUNDATION | 2021-02-25 | — | — | US | disclosed |
| US-20210053042-A1 | STRONGLY LEWIS ACIDIC METAL-ORGANIC FRAMEWORKS FOR CONTINUOUS FLOW CATALYSIS | NATIONAL SCIENCE FOUNDATION | 2021-02-25 | — | — | US | disclosed |
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2019-09-24 | — | — | US | disclosed |
| EP-3461816-A1 | FIVE-MEMBERED HETEROCYLIC COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20180118766-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-03 | — | — | US | disclosed |
| US-20170369447-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED | 2017-12-28 | — | — | US | disclosed |
| EP-3240543-A1 | BTK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109216-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| US-20150376136-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2015-12-31 | — | — | US | disclosed |
| EP-2958897-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130582-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| EP-0508292-B1 | Traction drive fluid, process for producing the same and bicyclo octane compound | IDEMITSU KOSAN CO (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5422027-A | Drive fluid for rotational elements having a torque transmission relationship comprising a bicyclooctane; low viscosity; broad temperature range; automobile transmissions | IDEMITSU KOSAN CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| US-5283384-A | Low viscosity | IDEMITSU KOSAN CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0508292-A1 | Traction drive fluid, process for producing the same and bicyclo octane compound | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-3967629-A | Bicyclic fragrance materials and processes therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12042788-B2 | Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis | CD69, TECR, MCM4 | KDM4E 1059/4885LMNA 3755/4885POLB 1804/4885 |
| US-10421727-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | KDM4E 4328/4885LMNA 4037/4885POLB 4409/4885 |
| US-20150376136-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPA1 | KDM4E 4328/4885LMNA 4037/4885POLB 4409/4885 |
| US-20180118766-A1 | BTK INHIBITORS | BTK, SYK, LYN | KDM4E 935/4885LMNA 4411/4885POLB 2417/4885 |
| US-20170369447-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPA1 | KDM4E 4328/4885LMNA 4037/4885POLB 4409/4885 |
| US-11028052-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPA1 | KDM4E 4328/4885LMNA 4037/4885POLB 4409/4885 |
| US-20210053042-A1 | STRONGLY LEWIS ACIDIC METAL-ORGANIC FRAMEWORKS FOR CONTINUOUS FLOW CATALYSIS | CD69, TECR, MCM4 | KDM4E 1059/4885LMNA 3755/4885POLB 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.