Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891954 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAPTL3MBTL1GAAATM | |
| SCHEMBL8996599 | 1.00 | SIGMAR1 (0.56) | SIGMAR1MAPTL3MBTL1GAAATM | |
| SCHEMBL536970 | 0.86 | PPID (0.55) | SIGMAR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL8936169 | 0.86 | PPID (0.55) | SIGMAR1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL4855884 | 0.85 | SMN1; SMN2 (0.44) | L3MBTL1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL4408805 | 0.85 | MEN1 (0.48) | SIGMAR1MAPTL3MBTL1ATMMEN1 | |
| SCHEMBL5394620 | 0.84 | SIGMAR1 (0.50) | SIGMAR1MAPTATMMEN1KMT2A | |
| SCHEMBL2852187 | 0.84 | SIGMAR1 (0.61) | SIGMAR1MAPTGAAMEN1KMT2A | |
| SCHEMBL4849306 | 0.84 | SIGMAR1 (0.61) | SIGMAR1MAPTGAAMEN1KMT2A | |
| SCHEMBL4855673 | 0.84 | SIGMAR1 (0.61) | SIGMAR1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3978471-A1 | NAPHTHALENESULFONAMIDE COMPOUND, PREPARATION METHOD, AND APPLICATION | China Pharmaceutical University (CN) | 2022-04-06 | — | — | EP | disclosed |
| EP-1594843-B1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE beta-amino acid derivative | TAKASAGO PERFUMERY CO LTD (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-8188307-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100036149-A1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE TETRAHYDROQUINOLINE | TAKASAGO INTERNATIONAL COPORATION (JP) | 2010-02-11 | — | — | US | disclosed |
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036149-A1 | METHOD FOR PRODUCING AN OPTICALLY ACTIVE TETRAHYDROQUINOLINE | AADAT, KMO, ALDH7A1 | SIGMAR1 2965/4885MAPT 4178/4885L3MBTL1 4666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.