Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993479 | 0.98 | ADRA2A (0.38) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL7610062 | 0.98 | ADRA2A (0.38) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL8374637 | 0.98 | ADRA2A (0.38) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL8009084 | 0.98 | ADRA2A (0.38) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL7611532 | 0.96 | MEN1 (0.37) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL27338495 | 0.79 | ADORA2B (0.47) | ADRA2ACNR2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8374647 | 0.79 | ADRA2A (0.37) | ADRA2ACNR2PTGER4LMNASMN1; SMN2 | |
| SCHEMBL8374665 | 0.79 | PTGER4 (0.44) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL8375311 | 0.79 | PTGER4 (0.44) | ADRA2ACNR2PTGER4PTGER1PTGER3 | |
| SCHEMBL7994402 | 0.79 | ACLY (0.33) | CNR2PTGER4PTGER1PTGER3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728003-A1 | METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA | CELL THERAPEUTICS, INC. (US) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013075-A1 | METHOD FOR PREVENTING TISSUE INJURY FROM HYPOXIA | CELL THERAPEUTICS, INC. (US) | 1995-05-18 | — | — | WO | disclosed |