SCHEMBL8996779

SCHEMBL8996779

C[Si](C)(C)OC=Cc1ccccc1.OC=Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.39
TRPA1 O75762 1/20 0.37
GLA P06280 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAOB P27338 1/20 0.37
CMA1 P23946 2/20 0.36
CYP1A2 P05177 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.35
HDAC3 O15379 1/20 0.35
TNKS O95271 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL770392 0.90 MAOB (0.44) ALOX15TRPA1GLATDP1MAOB
SCHEMBL10682846 0.78 MAOB (0.44) ALOX15TRPA1GLATDP1MAOB
SCHEMBL2777416 0.77
SCHEMBL28759603 0.77 MAOB (0.58) ALOX15TRPA1GLATDP1MAOB
SCHEMBL20077 0.77
Iodide SCHEMBL31264191 0.75 MAOB (0.55) ALOX15TRPA1GLATDP1MAOB
SCHEMBL29127335 0.75 MAOB (0.55) ALOX15TRPA1GLATDP1MAOB
Bromide SCHEMBL5434485 0.75 MAOB (0.55) ALOX15TRPA1GLATDP1MAOB
SCHEMBL5932034 0.74 CYP2C19 (0.40) ALOX15TRPA1GLATDP1MAOB
SCHEMBL456141 0.73 TRPA1 (0.44) ALOX15TRPA1MAOBCMA1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605856-B1 Process for the manufacture of p-hydroxystyrene polymers and use thereof BASF AG (DE) 1996-08-28 EP claimed
EP-0605856-A2 Process for the manufacture of p-hydroxystyrene polymers and use thereof BASF Aktiengesellschaft (DE) 1994-07-13 EP claimed