SCHEMBL770392

SCHEMBL770392

C[Si](C)(C)OC=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.44
TRPA1 O75762 2/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 1/20 0.41
CHAT P28329 2/20 0.40
ALDH1A1 P00352 3/20 0.39
RELA Q04206 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
NFE2L2 Q16236 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 1/20 0.38
GRM5 P41594 1/20 0.38
RAB9A P51151 1/20 0.38
GRM4 Q14833 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996779 0.90 ALOX15 (0.39) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL10682846 0.86 MAOB (0.44) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL456141 0.81 TRPA1 (0.44) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL8491011 0.80 NPC1 (0.48) MEN1KMT2AALOX15ALDH1A1KDM4E
SCHEMBL1899986 0.79 TRPA1 (0.38) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL19548024 0.79 RELA (0.43) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL8386348 0.78 NFE2L2 (0.48) TRPA1NFE2L2
SCHEMBL7541641 0.78 TRPA1 (0.45) MAOBTRPA1MEN1KMT2AALOX15
SCHEMBL8488639 0.78 AHR (0.43) MAOBMEN1KMT2AALDH1A1KDM4E
SCHEMBL5888604 0.77 RELA (0.44) MAOBTRPA1MEN1KMT2AALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1733211-A4 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS UNIV JOHNS HOPKINS (US) 2007-05-30 EP claimed
EP-1733211-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS-HOPKINS UNIVERSITY (US) 2006-12-20 EP claimed
WO-2005108473-A1 SEMICONDUCTOR NANOPARTICLE-ENCAPSULATING VINYL POLYMER, VINYL POLYMER MIXTURE INCLUDINGTHE SAME, AND PROCESS OF PREPARING THE SAME SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2005-11-17 WO claimed
WO-2005103655-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS HOPKINS UNIVERSITY (US) 2005-11-03 WO claimed
US-5914219-A Radiation-sensitive mixture and the production of relief structures having improved contrast BASF AKTIENGESELLSCHAFT (DE) 1999-06-22 US claimed
EP-0616258-B1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF AG (DE) 1997-05-21 EP claimed
EP-0605856-B1 Process for the manufacture of p-hydroxystyrene polymers and use thereof BASF AG (DE) 1996-08-28 EP claimed
EP-0616258-A1 Radiation sensitive composition and process for forming relief structures with improved contrast BASF Aktiengesellschaft (DE) 1994-09-21 EP claimed
WO-2024020780-A1 STAR-SHAPED POLYMER, PAINT, COATING, AND METHOD FOR PRODUCING STAR-SHAPED POLYMER DIC CORPORATION (JP) 2024-02-01 WO disclosed
CN-115997158-A Ophthalmic lens 株式会社目立康 2023-04-21 CN disclosed
WO-2023056310-A1 MOLECULARLY IMPRINTED POLYMER COATINGS AND SENSORS FOR BIODETECTION 6th Wave Innovations Corp. (US) 2023-04-06 WO disclosed
WO-2022236548-A1 STAR POLYMER, COATING MATERIAL, COATING FILM, AND METHOD FOR PRODUCING STAR POLYMER DIC CORPORATION (JP) 2022-11-17 WO disclosed
CN-107229185-B Energy-sensitive composition, cured product, and method for producing cured product 东京应化工业株式会社 2022-04-15 CN disclosed
CN-114051497-A Chromene compound and photochromic optical article 株式会社德山 2022-02-15 CN disclosed
EP-0277555-B1 COPOLYMERS WITH 0-NITROCARBINOL ESTER GROUPS, AND PROCESS FOR PREPARING TWO-LAYER RESISTS AND SEMICONDUCTOR DEVICES BASF Aktiengesellschaft (DE) 1992-04-08 EP disclosed
EP-0464614-A2 A composition having sensitivity to light or radiation MATSUSHITA ELECTRONICS CORPORATION (JP) 1992-01-08 EP disclosed
US-5073474-A Organic compound containing acid cleavable group(s) which also forms strong acid on irradiation, positive-working BASF AKTIENGESELLSCHAFT (DE) 1991-12-17 US disclosed
CN-1049660-A Aminoketone derivative and application thereof MITZUI TOATSU CHEMICALS INC (JP) 1991-03-06 CN disclosed
US-4808682-A BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
EP-0277555-A2 Copolymers with 0-nitrocarbinol ester groups, and process for preparing two-layer resists and semiconductor devices BASF Aktiengesellschaft (DE) 1988-08-10 EP disclosed