Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551482 | 0.78 | PTGS2 (0.46) | XDHPTGS1PTGS2GFERRIPK2 | |
| SCHEMBL8997236 | 0.72 | PTGS1 (0.39) | XDHPTGS1PTGS2GFERRIPK2 | |
| SCHEMBL60939 | 0.70 | KMT2A (0.71) | XDHRIPK2KMT2AKDM4EMEN1 | |
| Water SCHEMBL27782253 | 0.68 | NPSR1 (0.61) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10770387 | 0.68 | SMN1; SMN2 (0.48) | XDHPTGS1PTGS2GFERKMT2A | |
| SCHEMBL27498640 | 0.67 | CXCR2 (0.43) | KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL10365977 | 0.67 | RIPK2 (0.63) | RIPK2KDM4ESMN1; SMN2MAPK14SLC9A1 | |
| SCHEMBL10618154 | 0.67 | PTGS1 (0.68) | XDHPTGS1PTGS2GFERMAPK1 | |
| SCHEMBL10683662 | 0.67 | SMN1; SMN2 (0.47) | XDHPTGS1PTGS2GFERKMT2A | |
| SCHEMBL13967340 | 0.67 | KMT2A (0.51) | XDHPTGS2GFERKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486618-A | PLANT SAFENING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |
| EP-0561836-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010480-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |