Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551482 | 0.79 | PTGS2 (0.46) | PTGS1PTGS2KEAP1NFE2L2XDH | |
| SCHEMBL8997233 | 0.78 | PTGS1 (0.40) | PTGS1PTGS2KEAP1NFE2L2FPR1 | |
| SCHEMBL8997240 | 0.74 | PTGS1 (0.48) | PTGS1PTGS2FPR1GFER | |
| SCHEMBL8997223 | 0.72 | XDH (0.46) | PTGS1PTGS2KEAP1NFE2L2XDH | |
| SCHEMBL60939 | 0.61 | KMT2A (0.71) | XDHSMN1; SMN2RIPK2 | |
| SCHEMBL10770387 | 0.59 | SMN1; SMN2 (0.48) | PTGS1PTGS2XDHGFERSMN1; SMN2 | |
| SCHEMBL3491956 | 0.59 | KEAP1 (0.86) | KEAP1NFE2L2SLC9A1SLC9A2 | |
| SCHEMBL2925940 | 0.59 | FPR1 (0.64) | PTGS2FPR1SLC9A1SLC9A2SMN1; SMN2 | |
| SCHEMBL10365977 | 0.58 | RIPK2 (0.63) | KEAP1NFE2L2SLC9A1SLC9A2SMN1; SMN2 | |
| SCHEMBL10618154 | 0.58 | PTGS1 (0.68) | PTGS1PTGS2XDHGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486618-A | PLANT SAFENING AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |
| EP-0561836-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010480-A1 | SUBSTITUTED 5-AMINOPYRAZOLS | BASF AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |