SCHEMBL5147607

SCHEMBL5147607

CC(=O)NS(=O)(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.54
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
EDNRB P24530 4/20 0.47
EDNRA P25101 4/20 0.47
KDM4E B2RXH2 1/20 0.47
PTGS2 P35354 1/20 0.44
PKM P14618 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
DHFR P00374 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
BCAT1 P54687 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2967725 0.89 KDM4E (0.47) CASP1EDNRBEDNRAKDM4ECA2
SCHEMBL2967723 0.87 CASP1 (0.43) CASP1HSP90AA1HSP90AB1KDM4EPKM
SCHEMBL8240985 0.86 CASP1 (0.56) CASP1EDNRBEDNRACA1CA2
SCHEMBL10916572 0.83 CASP1 (0.51) CASP1EDNRBEDNRATDP1
SCHEMBL7023007 0.83 CASP1 (0.54) CASP1EDNRBEDNRACA1CA2
SCHEMBL1767981 0.80 CA2 (0.58) CASP1EDNRBEDNRAPTGS2CA1
SCHEMBL29537027 0.80 CA2 (0.58) CASP1EDNRBEDNRAPTGS2CA1
SCHEMBL8997291 0.79 CASP1 (0.50) CASP1EDNRBEDNRACA1CA2
SCHEMBL7021598 0.79 GAA (0.48) CASP1EDNRBEDNRA
SCHEMBL1846856 0.78 CASP1 (0.51) CASP1EDNRBEDNRAPTGS2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-20040043325-A1 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2004-03-04 US disclosed
EP-1391784-A2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. (JP) 2004-02-25 EP disclosed