Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP12 | P39900 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 4/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387450 | 0.89 | MMP2 (0.57) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL28158988 | 0.85 | MMP2 (0.53) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL31387895 | 0.84 | MMP2 (0.52) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL7357393 | 0.80 | MME (0.60) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL7357412 | 0.80 | MME (0.60) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL31512922 | 0.79 | CTSK (0.56) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL15223639 | 0.79 | MME (0.66) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL2873585 | 0.79 | MME (0.62) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL31512916 | 0.78 | REN (0.59) | MMP2MMP7MMP9MMP12MMP13 | |
| SCHEMBL9387432 | 0.78 | MME (0.61) | MMP2MMP7MMP9MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570352-B1 | Novel hexapeptide | UNIV WASHINGTON (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0570352-A1 | Novel hexapeptide | WASHINGTON UNIVERSITY (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5225531-A | Ligand binding specificity of the leukocyte response integrin expressed by human neutrophils | WASHINGTON UNIVERSITY (US) | 1993-07-06 | — | — | US | disclosed |