Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.42 |
| ▸ | ALAD | P13716 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163167 | 0.94 | LMNA (0.62) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6367 | 0.94 | LMNA (0.62) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6366 | 0.94 | LMNA (0.62) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29903923 | 0.94 | LMNA (0.62) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11652701 | 0.91 | LMNA (0.60) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| Chlorobenzene SCHEMBL8754828 | 0.88 | LMNA (0.68) | LMNAMAPK1CYP2C9CYP2C19MEN1 | |
| SCHEMBL7566668 | 0.86 | LMNA (0.54) | LMNAMAPK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7564005 | 0.83 | LMNA (0.74) | LMNAMAPK1FFAR1CYP1A2CYP2C9 | |
| SCHEMBL8993579 | 0.83 | LMNA (0.74) | LMNAMAPK1FFAR1CYP1A2CYP2C9 | |
| SCHEMBL7564021 | 0.83 | LMNA (0.74) | LMNAMAPK1FFAR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459455-B1 | Process for producing optically active alpha-hydroxyesters | CHISSO CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5248610-A | Transesterification | CHISSO CORPORATION (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0459455-A2 | Process for producing optically active alpha-hydroxyesters | CHISSO CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |