Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564005 | 1.00 | LMNA (0.74) | LMNAMAPK1PTGS2ACP3CES2 | |
| SCHEMBL7564021 | 1.00 | LMNA (0.74) | LMNAMAPK1PTGS2ACP3CES2 | |
| Mandelic Acid SCHEMBL5313046 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| Mandelic Acid SCHEMBL1050 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| Mandelic Acid SCHEMBL21647917 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| Mandelic Acid SCHEMBL165161 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| Mandelic Acid SCHEMBL255601 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| Mandelic Acid SCHEMBL29777368 | 0.85 | LMNA (1.00) | LMNAMAPK1CES2CES1PKM | |
| SCHEMBL275597 | 0.85 | LMNA (0.79) | LMNAMAPK1PTGS2CES2CES1 | |
| SCHEMBL8997286 | 0.84 | LMNA (0.58) | LMNAMAPK1PTGS2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504108-A | ANTIAGGLOMERANTS, ANTIARTHRITIC AGENTS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |