Styrene

Styrene

SCHEMBL8997402

C=C(C)C(=O)Oc1ccc(C)cc1.C=Cc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.57
LMNA P02545 1/20 0.46
KMT2A Q03164 4/20 0.43
ATM Q13315 1/20 0.43
ALDH1A1 P00352 4/20 0.41
TSHR P16473 1/20 0.41
MAPT P10636 2/20 0.39
PPARG P37231 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
CYP1B1 Q16678 1/20 0.39
PTK2B Q14289 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8073704 0.94 ELANE (0.64) ELANEKMT2AATMALDH1A1TSHR
Styrene SCHEMBL544781 0.91 ELANE (0.59) ELANEKMT2AATMALDH1A1TSHR
Styrene SCHEMBL28234664 0.91 ELANE (0.59) ELANEKMT2AATMALDH1A1TSHR
Styrene SCHEMBL16660458 0.88 ELANE (0.57) ELANELMNAKMT2AATMALDH1A1
Styrene SCHEMBL209287 0.88 ELANE (0.56) ELANEKMT2AATMALDH1A1TSHR
SCHEMBL5831972 0.86 ELANE (0.56) ELANELMNAKMT2AATMALDH1A1
SCHEMBL146180 0.84 LMNA (0.63) ELANELMNAKMT2AATMALDH1A1
Styrene SCHEMBL8166038 0.84 ALDH1A1 (0.46) ELANELMNAKMT2AALDH1A1TSHR
Methacrylic Acid SCHEMBL28515155 0.82 ELANE (0.60) ELANELMNAKMT2AATMALDH1A1
SCHEMBL544782 0.81 ELANE (0.64) ELANELMNAKMT2AATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458082-B1 Encapsulated toner compositions XEROX CORP (US) 1996-09-04 EP claimed