Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15270696 | 0.83 | MAPT (0.43) | CYP1A2ALDH1A1CYP3A4KMT2AHPGD | |
| SCHEMBL7447940 | 0.83 | CYP1A2 (0.44) | CYP1A2ALDH1A1KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7512534 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3091554 | 0.82 | CYP1A2 (0.52) | CYP1A2ALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL7512529 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8997426 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL8030864 | 0.81 | CYP1A2 (0.47) | CYP1A2ALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL12571904 | 0.81 | CYP1A2 (0.44) | CYP1A2ALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL25439358 | 0.81 | CYP1A2 (0.46) | CYP1A2ALDH1A1CYP3A4KMT2ATSHR | |
| SCHEMBL8019577 | 0.81 | CYP1A2 (0.46) | CYP1A2ALDH1A1CYP3A4TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459455-B1 | Process for producing optically active alpha-hydroxyesters | CHISSO CORP (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5248610-A | Transesterification | CHISSO CORPORATION (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0459455-A2 | Process for producing optically active alpha-hydroxyesters | CHISSO CORPORATION (JP) | 1991-12-04 | — | — | EP | disclosed |