Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997416 | 0.83 | CYP1A2 (0.49) | CYP1A2KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7437148 | 0.83 | CA1 (0.46) | KMT2ASMN1; SMN2 | |
| SCHEMBL5918040 | 0.83 | L3MBTL1 (0.46) | L3MBTL1 | |
| SCHEMBL7434531 | 0.83 | KMT2A (0.45) | KMT2AALDH1A1F2PRSS1PRSS2 | |
| SCHEMBL2488220 | 0.82 | KMT2A (0.58) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL2485143 | 0.82 | KMT2A (0.58) | KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6621061 | 0.81 | ENPP3 (0.41) | KMT2AALDH1A1 | |
| SCHEMBL20943223 | 0.77 | CYP1A2 (0.48) | CYP1A2KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL999785 | 0.76 | ALDH1A1 (0.56) | CYP1A2KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11596920 | 0.76 | CYP1A2 (0.52) | CYP1A2KMT2AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |