Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.45 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997541 | 1.00 | NPFFR2 (0.45) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL8918957 | 0.89 | ALDH1A1 (0.41) | KDRHDAC1HDAC8HDAC6TDP1 | |
| SCHEMBL8918971 | 0.89 | ALDH1A1 (0.41) | KDRHDAC1HDAC8HDAC6TDP1 | |
| SCHEMBL8120081 | 0.85 | NPFFR1 (0.45) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL8034221 | 0.85 | NPFFR1 (0.45) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL4800117 | 0.82 | NPFFR1 (0.49) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL2908923 | 0.82 | NPFFR1 (0.49) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL4800123 | 0.82 | NPFFR1 (0.49) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL1720610 | 0.80 | NPFFR2 (0.53) | NPFFR2NPFFR1KDRHDAC1HDAC8 | |
| SCHEMBL2907979 | 0.80 | KDR (0.44) | NPFFR2NPFFR1KDRHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559139-A | ANTIISCHEMIC AGENTS, MICROCIRCULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |