Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HCN1 | O60741 | 1/20 | 0.35 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583793 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BCXCR5HDAC1HDAC6 | |
| SCHEMBL8583790 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BCXCR5HDAC1HDAC6 | |
| SCHEMBL8584280 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BCXCR5HDAC1HDAC6 | |
| SCHEMBL8599195 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BHDAC1HDAC6ADRA2A | |
| SCHEMBL8598490 | 0.74 | MTNR1A (0.51) | MTNR1AMTNR1BHDAC1HDAC6ADRA2A | |
| SCHEMBL8845587 | 0.71 | MTNR1A (0.45) | MTNR1AMTNR1BCXCR5ADRA2ANPC1 | |
| SCHEMBL8596061 | 0.70 | MMP1 (0.48) | MTNR1AMTNR1B | |
| SCHEMBL8424174 | 0.70 | CXCR5 (0.50) | CXCR5 | |
| SCHEMBL8424334 | 0.70 | CXCR5 (0.50) | CXCR5 | |
| SCHEMBL8422478 | 0.70 | CXCR5 (0.50) | CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729972-A1 | Peptide derivatives of tetrahydronaphthalene | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-04 | — | — | EP | disclosed |