Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583793 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BADRA2ACXCR5KCNK3 | |
| SCHEMBL8584280 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BADRA2ACXCR5KCNK3 | |
| SCHEMBL8583790 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BADRA2ACXCR5KCNK3 | |
| SCHEMBL5835214 | 0.77 | GHSR (0.53) | MTNR1AMTNR1BADRA2ACYP1A2MAPT | |
| SCHEMBL5835478 | 0.76 | ADRA2A (0.46) | MTNR1AMTNR1BADRA2ACYP1A2MAPT | |
| SCHEMBL5836253 | 0.75 | GHSR (0.48) | MTNR1AMTNR1BADRA2ACYP1A2MAPT | |
| SCHEMBL5835134 | 0.73 | ADRA2A (0.48) | MTNR1AMTNR1BADRA2ACYP1A2MAPT | |
| SCHEMBL7917604 | 0.72 | ADRA2A (0.47) | MTNR1AMTNR1BADRA2ACYP1A2MAPT | |
| SCHEMBL8997570 | 0.71 | MTNR1A (0.46) | MTNR1AMTNR1BADRA2ACXCR5NPC1 | |
| SCHEMBL5835267 | 0.70 | ADRA2A (0.43) | MTNR1AMTNR1BADRA2ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644024-A | MIMICS OF PEPTIDE DOMAINS, SEQUENCE DETERMINATION, DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |