Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997714 | 0.82 | HTR2C (0.31) | HTR2CPARP1MTNR1AMTNR1B | |
| SCHEMBL15445089 | 0.71 | OPRM1 (0.31) | — | |
| SCHEMBL13649226 | 0.71 | DRD2 (0.39) | HTR2CMTNR1AMTNR1B | |
| SCHEMBL18586357 | 0.64 | ALDH1A1 (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL31406729 | 0.64 | ALDH1A1 (0.40) | HTR2CHTR2AHTR2B | |
| SCHEMBL4198450 | 0.64 | HTR2C (0.52) | HTR2CHTR2AHTR2B | |
| SCHEMBL25707311 | 0.60 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL25228077 | 0.59 | HTR2A (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL8255961 | 0.59 | HTR2C (0.41) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL30041588 | 0.58 | MAP4K1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547960-A | ACETYLCHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1996-08-20 | — | — | US | disclosed |