Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924440 | 0.71 | RORC (0.37) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL31397659 | 0.71 | RORC (0.37) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL7926425 | 0.66 | HTR1A (0.49) | MTNR1AMTNR1BHTR1A | |
| SCHEMBL7952626 | 0.60 | BRD4 (0.40) | — | |
| SCHEMBL8997714 | 0.60 | HTR2C (0.31) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL18231269 | 0.59 | TLR4 (0.34) | HTR1A | |
| SCHEMBL11934303 | 0.57 | KMT2A (0.37) | — | |
| SCHEMBL17656944 | 0.56 | DRD2 (0.40) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL8116003 | 0.56 | SRD5A1 (0.47) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL50426 | 0.56 | KDM4E (0.49) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547960-A | ACETYLCHOLINESTERASE INHIBITORS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1996-08-20 | — | — | US | disclosed |