Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265203 | 0.86 | L3MBTL1 (0.50) | HRH1KDM4ELMNAL3MBTL1 | |
| SCHEMBL9273006 | 0.85 | DRD2 (0.56) | HRH1KDM4EDRD2DRD1LMNA | |
| SCHEMBL9268725 | 0.84 | L3MBTL1 (0.48) | HRH1KDM4EL3MBTL1 | |
| SCHEMBL3485836 | 0.83 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL9003138 | 0.83 | HRH1 (0.61) | HRH1KDM4EDRD2DRD1DRD4 | |
| SCHEMBL11396736 | 0.82 | HRH1 (0.57) | HRH1KDM4EDRD2DRD1DRD4 | |
| SCHEMBL2406964 | 0.81 | PPARG (0.56) | LMNAL3MBTL1 | |
| SCHEMBL8084869 | 0.81 | L3MBTL1 (0.57) | L3MBTL1 | |
| SCHEMBL8080247 | 0.80 | MEN1 (0.57) | LMNAL3MBTL1 | |
| SCHEMBL8072236 | 0.80 | MEN1 (0.57) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508433-A | Derivatives of perhydroisoindole and preparation thereof | RHONE-POULENC RORER S.A. (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5484942-A | Thiopyranopyrrole derivatives | RHONE-POULENC RORER S.A. (FR) | 1996-01-16 | — | — | US | disclosed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |