Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896068 | 0.82 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7432481 | 0.76 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7432476 | 0.76 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| Benzoic Acid SCHEMBL28932601 | 0.76 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1070286 | 0.75 | MEN1 (0.53) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| Diethyl Maleate SCHEMBL11324124 | 0.75 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL14186862 | 0.75 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| Benzoic Acid SCHEMBL28164446 | 0.75 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL20109337 | 0.75 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9751109 | 0.74 | MAPT (0.72) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |