Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998111 | 0.90 | MAOA (0.39) | ALDH1A1RECQLLMNATSHRNPSR1 | |
| SCHEMBL9407131 | 0.79 | ALDH1A1 (0.48) | ALDH1A1RECQLLMNATSHRNPSR1 | |
| SCHEMBL7220721 | 0.77 | ALDH1A1 (0.54) | ALDH1A1RECQLTSHRKCNQ2KCNQ4 | |
| SCHEMBL10576902 | 0.77 | P2RX3 (0.46) | ALDH1A1RECQLLMNATSHRNPSR1 | |
| SCHEMBL8083816 | 0.77 | ALDH1A1 (0.46) | ALDH1A1RECQLLMNATSHRNPSR1 | |
| SCHEMBL8998078 | 0.77 | CYP2B6 (0.44) | ALDH1A1LMNATSHRNPSR1L3MBTL1 | |
| SCHEMBL24170851 | 0.76 | SMN1; SMN2 (0.53) | ALDH1A1TSHRKCNQ2KCNQ4CYP1A2 | |
| SCHEMBL8084401 | 0.75 | ALDH1A1 (0.51) | ALDH1A1RECQLTSHRKCNQ2KCNQ4 | |
| SCHEMBL24961026 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TSHRNPSR1KCNQ2KCNQ4 | |
| SCHEMBL16774399 | 0.74 | DHODH (0.45) | ALDH1A1LMNATSHRSMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |