Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407131 | 0.85 | ALDH1A1 (0.48) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9427678 | 0.82 | ALDH1A1 (0.52) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8760807 | 0.82 | POLB (0.43) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9426916 | 0.81 | MEN1 (0.52) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9407130 | 0.81 | L3MBTL1 (0.62) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8998085 | 0.80 | LMNA (0.38) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8083816 | 0.80 | ALDH1A1 (0.46) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9427481 | 0.80 | LMNA (0.39) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9427488 | 0.80 | LMNA (0.39) | LMNANPSR1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8998058 | 0.79 | LMNA (0.34) | LMNANPSR1ALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |