SCHEMBL8998629

SCHEMBL8998629

FC(F)(F)C(F)(F)C(F)(F)N(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7561478 1.00 LMNA (0.35) LMNACA1CA2MMP1MMP2
SCHEMBL36219 0.96 LMNA (0.37) LMNACA1CA2MMP1MMP2
SCHEMBL195985 0.93 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL9358020 0.93 LMNA (0.35) LMNACA1CA2MMP1MMP2
SCHEMBL14717610 0.93 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL9546264 0.93 LMNA (0.35) LMNACA1CA2MMP1MMP2
SCHEMBL480135 0.93 LMNA (0.42) LMNACA1CA2MMP1MMP2
SCHEMBL17111382 0.93 LMNA (0.42) LMNACA1CA2MMP1MMP2
Water SCHEMBL11135872 0.93 LMNA (0.35) LMNACA1CA2MMP1MMP2
SCHEMBL78572 0.93 LMNA (0.42) LMNACA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612765-B1 Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants DU PONT (US) 1996-12-04 EP disclosed
EP-0608802-B1 Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids DU PONT (US) 1996-09-04 EP disclosed
EP-0612765-A2 Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-31 EP disclosed
EP-0608802-A2 Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-08-03 EP disclosed
US-5242987-A Process for chlorination and chlorosulfonation of olefin polymers in suspensions of perfluorinated liquids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed
US-5242988-A Process for chlorination and chlorosulfonation of olefin polymers in the presence of fluorinated surfactants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-07 US disclosed