SCHEMBL8998711

SCHEMBL8998711

CCCCCCCCc1ccc(-c2cc3ccccc3[nH]2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 3/20 0.68
CTSL P07711 3/20 0.68
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
KDM4E B2RXH2 2/20 0.53
MAPT P10636 2/20 0.53
CASP3 P42574 2/20 0.53
SENP8 Q96LD8 2/20 0.53
SENP7 Q9BQF6 2/20 0.53
SENP6 Q9GZR1 2/20 0.53
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
HPGD P15428 1/20 0.53
CYP2C19 P33261 1/20 0.53
KMT2A Q03164 1/20 0.53
GPR84 Q9NQS5 2/20 0.52
APP P05067 2/20 0.49
MMP2 P08253 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10513486 1.00 CTSV (0.68) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL27821692 0.94 CTSV (0.67) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL24988943 0.83 PPARG (0.58) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL8025177 0.82 RAB9A (0.65) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL10514160 0.81 CTSV (0.63) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL10514020 0.81 CTSV (0.63) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL11658586 0.80 MAPT (0.48) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL17965673 0.80 CTSV (0.55) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL11725377 0.80 NPC1 (0.50) CTSVCTSLNPC1RAB9AKDM4E
SCHEMBL22245761 0.79 KDM4E (0.51) CTSVCTSLNPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0483400-B1 Stabilized chlorinated resin composition ASAHI DENKA KOGYO KK (JP) 1996-09-11 EP disclosed
US-5356981-A An inorganic copper compound adsorbed into hydrotalcite; polyvinyl chloride ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1994-10-18 US disclosed
EP-0483400-A1 Stabilized chlorinated resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1992-05-06 EP disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
EP-0212559-A2 Stabilizer compositions for polyvinyl chloride resins and stabilized polyvinyl chloride resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-03-04 EP disclosed