SCHEMBL8998746

SCHEMBL8998746

CC(C)=CCCC(C)CCC/C(C)=C/CO

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.69
ALOX15 P16050 4/20 0.58
ALDH1A1 P00352 2/20 0.58
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
CYP3A4 P08684 2/20 0.57
MAPT P10636 2/20 0.55
UGT1A1 P22309 1/20 0.55
SQLE Q14534 4/20 0.46
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8319131 1.00 PTPN1 (0.69) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL27414779 0.98 PTPN1 (0.72) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL27414782 0.95 ALOX15 (0.65) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL17244805 0.95 ALOX15 (0.65) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL27414783 0.95 ALOX15 (0.65) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL28885971 0.94 PTPN1 (0.66) PTPN1ALOX15ALDH1A1KMT2AMEN1
SCHEMBL27414780 0.88 PTPN1 (0.83) PTPN1ALOX15ALDH1A1KMT2AMEN1
Trans-Phytol SCHEMBL4063116 0.85 PTPN1 (0.79) PTPN1ALOX15ALDH1A1KMT2AMEN1
Trans-Phytol SCHEMBL2066043 0.85 PTPN1 (0.79) PTPN1ALOX15ALDH1A1KMT2AMEN1
Squalene SCHEMBL29131843 0.84 PTPN1 (0.77) PTPN1ALOX15ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365905-B2 Host cells and methods for reducing isoprenoid precursors and isoprenoids by geranylgeranyl reductase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-22 US disclosed
US-20240209132-A1 COUPLING OF 2,3,5-TRIMETHYLHYDROQUINONE AND UNSATURATED ALCOHOLS DSM IP ASSETS B.V. (NL) 2024-06-27 US disclosed
US-20220396823-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION TUMOREND, LLC (US) 2022-12-15 US disclosed
US-11203776-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration TUMOREND, LLC (US) 2021-12-21 US disclosed
US-20200255841-A1 HOST CELLS AND METHODS FOR REDUCING ISOPRENOID PRECURSORS AND ISOPRENOIDS BY GERANYLGERANYL REDUCTASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-13 US disclosed
US-20190017095-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION TUMOREND, LLC (US) 2019-01-17 US disclosed
WO-2016077567-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION TUMOREND, LLC (US) 2016-05-19 WO disclosed
US-20130158106-A1 TOCOPHEROL DERIVATIVES AND METHODS OF USE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (US) 2013-06-20 US disclosed
US-20130158106-A1 TOCOPHEROL DERIVATIVES AND METHODS OF USE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (US) 2013-06-20 US disclosed
EP-1793796-B1 USE OF AROMA SUBSTANCE MIXTURES AS AGENTS AGAINST BAD BREATH SYMRISE GMBH & CO KG (DE) 2009-12-09 EP disclosed
US-20070218016-A1 Use of Aroma Substance Mixtures as Agents Against Bad Breath SYMRISE GMBH & CO. KG (DE) 2007-09-20 US disclosed
EP-0258967-B2 Process for producing optically active alcohols TAKASAGO PERFUMERY CO LTD (JP) 1996-08-21 EP disclosed
US-4962242-A HYDROGENATING OLEFINIC ALCOHOL USING AS CATALYST A RUTHENIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX TAKASAGO PERFUMERY CO., LTD. (JP) 1990-10-09 US disclosed
EP-0258967-A2 Process for producing optically active alcohols Takasago Perfumery Co., Ltd. (JP) 1988-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220396823-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION SIGLEC7, SIGLEC9, HAVCR2 PTPN1 1410/4885ALOX15 592/4885ALDH1A1 1675/4885
US-11203776-B2 Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration SIGLEC7, SIGLEC9, HAVCR2 PTPN1 1410/4885ALOX15 592/4885ALDH1A1 1675/4885
US-20130158106-A1 TOCOPHEROL DERIVATIVES AND METHODS OF USE TTPA, OSBP, PCTP PTPN1 4876/4885ALOX15 267/4885ALDH1A1 1927/4885
US-20190017095-A1 COMPOSITIONS, METHODS AND TREATMENTS FOR INHIBITING CELL ADHESION AND VIRUS BINDING AND PENETRATION SIGLEC7, SIGLEC9, HAVCR2 PTPN1 1410/4885ALOX15 592/4885ALDH1A1 1675/4885
US-20070218016-A1 Use of Aroma Substance Mixtures as Agents Against Bad Breath BAD, BAX, BAK1 PTPN1 4340/4885ALOX15 2594/4885ALDH1A1 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.