Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TK1 | P04183 | 3/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2056775 | 1.00 | POLB (0.61) | POLBTK1BCHE | |
| SCHEMBL9843866 | 0.89 | TK1 (0.54) | TK1BCHE | |
| SCHEMBL9843870 | 0.89 | TK1 (0.54) | TK1BCHE | |
| SCHEMBL12344083 | 0.88 | POLB (0.56) | POLBTK1 | |
| SCHEMBL263767 | 0.88 | POLB (0.64) | POLBTK1 | |
| SCHEMBL15216188 | 0.88 | POLB (0.64) | POLBTK1 | |
| SCHEMBL3694340 | 0.88 | POLB (0.64) | POLBTK1BCHE | |
| SCHEMBL263768 | 0.88 | POLB (0.64) | POLBTK1 | |
| SCHEMBL17224728 | 0.88 | POLB (0.59) | POLBTK1 | |
| SCHEMBL14063693 | 0.88 | POLB (0.59) | POLBTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443115-A | Process for preparing zidovudine and intermediates thereof | SHANGHAI DESANO PHARMACEUTICALS INVEST CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-103443115-A | Process for preparing zidovudine and intermediates thereof | SHANGHAI DESANO PHARMACEUTICALS INVEST CO LTD | 2013-12-11 | — | — | CN | disclosed |
| US-5495009-A | TREATING WITH BROMINE IN PRESENCE OF 2,6-DIETHYLPYRIDINE AND MOLECULAR SIEVES FOLLOWED BY TREATMENT WITH TETRABUTYLAMMONIUM FLUORIDE IN TETRAHYDROFURAN | GILEAD SCIENCES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5264562-A | Replacement of phosphodiester linkages with some acetal/ketal type, resistant to nuclease digestion | GILEAD SCIENCES, INC. (US) | 1993-11-23 | — | — | US | disclosed |
| WO-1992019637-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING THIOFORMACETAL LINKAGES | GILEAD SCIENCES, INC. (US) | 1992-11-12 | — | — | WO | disclosed |