SCHEMBL2056775

SCHEMBL2056775

Cc1cn([C@H]2C[C@H](O)[C@@H](COC(=O)C(C)(C)C)O2)c(=O)[nH]c1=O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.61
TK1 P04183 3/20 0.58
BCHE P06276 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8999366 1.00 POLB (0.61) POLBTK1BCHE
SCHEMBL9843866 0.89 TK1 (0.54) TK1BCHE
SCHEMBL9843870 0.89 TK1 (0.54) TK1BCHE
SCHEMBL12344083 0.88 POLB (0.56) POLBTK1
SCHEMBL263767 0.88 POLB (0.64) POLBTK1
SCHEMBL15216188 0.88 POLB (0.64) POLBTK1
SCHEMBL3694340 0.88 POLB (0.64) POLBTK1BCHE
SCHEMBL263768 0.88 POLB (0.64) POLBTK1
SCHEMBL17224728 0.88 POLB (0.59) POLBTK1
SCHEMBL14063693 0.88 POLB (0.59) POLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110104754-A1 CELL CULTURE MEDIUM GENETIX LIMITED 2011-05-05 US disclosed
EP-1818392-B1 Cell culture medium GENETIX LTD (GB) 2010-08-25 EP disclosed
US-20070212778-A1 Cell culture medium GENETIX LIMITED 2007-09-13 US disclosed
EP-1818392-A1 Cell culture medium Genetix Limited (GB) 2007-08-15 EP disclosed
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORPORATION (US) 2004-09-30 US disclosed
US-6743782-B1 ACYL DERIVATIVE OF 2'-DEOXYADENOSINE; TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED CELLULAR DAMAGE, IMPROVING WOUND HEALING AND TISSUE REPAIR, AMELIORATING THE EFFECTS OF AGING; ENHANCE BIOAVAILABILITY WELLSTAT THERAPEUTICS CORPORATION 2004-06-01 US disclosed
US-6020320-A Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040192635-A1 Acyl deoxyribonucleoside derivatives and uses thereof UNG, OGG1, NQO1 POLB 46/4885TK1 489/4885BCHE 4023/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.